Curcumin stably interacts with DNA hairpin through minor groove binding and demonstrates enhanced cytotoxicity in combination with FdU nucleotides. [electronic resource]
Producer: 20180522Description: 485-494 p. digitalISSN:- 0304-4165
- Anticarcinogenic Agents -- chemistry
- Antineoplastic Agents, Phytogenic -- chemistry
- Apoptosis -- drug effects
- Cell Line, Tumor
- Circular Dichroism
- Curcumin -- chemistry
- DNA -- drug effects
- Drug Synergism
- Floxuridine -- metabolism
- Humans
- Models, Molecular
- Molecular Dynamics Simulation
- Nuclear Magnetic Resonance, Biomolecular
- Nucleic Acid Conformation -- drug effects
- Spectrometry, Fluorescence
- Spectrophotometry, Ultraviolet
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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