Ethyl pyruvate reduces acute lung damage following trauma and hemorrhagic shock via inhibition of NF-κB and HMGB1. [electronic resource]
Producer: 20190111Description: 310-318 p. digitalISSN:- 1878-3279
- Acute Lung Injury -- drug therapy
- Animals
- Anti-Inflammatory Agents -- therapeutic use
- Disease Models, Animal
- Gene Expression Regulation
- HMGB1 Protein -- metabolism
- Humans
- Lung -- drug effects
- NF-kappa B -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Pyruvates -- therapeutic use
- Rats
- Rats, Inbred Lew
- Shock, Hemorrhagic -- diet therapy
- Signal Transduction -- drug effects
- Thoracic Injuries -- drug therapy
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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