Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. [electronic resource]
Producer: 20171229Description: 9807-9820 p. digitalISSN:- 1520-4804
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Animals
- Aspartic Acid Endopeptidases -- antagonists & inhibitors
- Brain -- metabolism
- Crystallography, X-Ray
- Cyclization
- Drug Design
- Ethylamines -- chemistry
- Humans
- Magnetic Resonance Spectroscopy
- Mice
- Models, Molecular
- Morpholines -- chemistry
- Peptides -- chemistry
- Protease Inhibitors -- chemistry
- Structure-Activity Relationship
No physical items for this record
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.