Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice. [electronic resource]
Producer: 20171107Description: 2797-2805 p. digitalISSN:- 1460-2156
- Amyotrophic Lateral Sclerosis -- genetics
- Animals
- Disease Models, Animal
- Endoplasmic Reticulum, Rough -- metabolism
- Frameshift Mutation
- Gene Dosage
- Gene Expression Profiling
- Gene Knock-In Techniques
- Heterozygote
- Humans
- Mice
- Mitochondria -- metabolism
- Motor Neurons -- metabolism
- Neuromuscular Junction -- metabolism
- Protein Aggregation, Pathological -- genetics
- RNA-Binding Protein FUS -- genetics
- Ribosomal Proteins -- genetics
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Publication Type: Journal Article
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