Fenofibrate decreases the bone quality by down regulating Runx2 in high-fat-diet induced Type 2 diabetes mellitus mouse model. [electronic resource]
Producer: 20180625Description: 201 p. digitalISSN:- 1476-511X
- Animals
- Bone Density -- drug effects
- Caspase 3 -- genetics
- Collagen Type I -- genetics
- Core Binding Factor Alpha 1 Subunit -- antagonists & inhibitors
- Diabetes Mellitus, Type 2 -- etiology
- Diet, High-Fat -- adverse effects
- Disease Models, Animal
- Dyslipidemias -- etiology
- Fenofibrate -- adverse effects
- Gene Expression Regulation
- Humans
- Hypolipidemic Agents -- adverse effects
- Mice
- Osteoblasts -- drug effects
- Osteocalcin -- genetics
- Porosity -- drug effects
- Primary Cell Culture
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Signal Transduction
- X-Ray Microtomography
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Publication Type: Journal Article
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