Simultaneous determination of a novel c-Met/AXL dual-target small-molecule inhibitor BPI-9016M and its metabolites in human plasma by liquid chromatography-tandem mass spectrometry: Application in a pharmacokinetic study in Chinese advanced solid tumor patients. [electronic resource]
Producer: 20171204Description: 33-40 p. digitalISSN:- 1873-376X
- Antineoplastic Agents -- therapeutic use
- Chromatography, Liquid -- methods
- Drug Stability
- Humans
- Linear Models
- Neoplasms -- drug therapy
- Protein Kinase Inhibitors -- therapeutic use
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Proto-Oncogene Proteins c-met -- antagonists & inhibitors
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Reproducibility of Results
- Sensitivity and Specificity
- Tandem Mass Spectrometry -- methods
- Axl Receptor Tyrosine Kinase
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Publication Type: Journal Article
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