TSPYL Family Regulates CYP17A1 and CYP3A4 Expression: Potential Mechanism Contributing to Abiraterone Response in Metastatic Castration-Resistant Prostate Cancer. [electronic resource]
Producer: 20190705Description: 201-210 p. digitalISSN:- 1532-6535
- Abiraterone Acetate -- pharmacology
- Cell Cycle Proteins -- drug effects
- Cell Proliferation -- drug effects
- Cytochrome P-450 CYP3A -- drug effects
- Cytochrome P-450 Enzyme Inhibitors -- pharmacology
- DNA-Binding Proteins
- Dehydroepiandrosterone -- metabolism
- Gene Expression Regulation -- drug effects
- Gene Knockdown Techniques
- Hep G2 Cells
- Humans
- Male
- Neoplasm Metastasis
- Nuclear Proteins -- drug effects
- Proportional Hazards Models
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- RNA, Messenger -- metabolism
- Steroid 17-alpha-Hydroxylase -- antagonists & inhibitors
- Treatment Outcome
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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