Sub-therapeutic doses of fluvastatin and valsartan are more effective than therapeutic doses in providing beneficial cardiovascular pleiotropic effects in rats: A proof of concept study. [electronic resource]
Producer: 20171212Description: 45-52 p. digitalISSN:- 1879-3649
- Angiotensin II Type 1 Receptor Blockers -- administration & dosage
- Animals
- Aorta, Thoracic -- drug effects
- Arginine -- analogs & derivatives
- Blood Pressure -- drug effects
- Cholesterol -- blood
- Coronary Circulation -- drug effects
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Therapy, Combination
- Fatty Acids, Monounsaturated -- administration & dosage
- Female
- Fluvastatin
- Heart -- drug effects
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- administration & dosage
- In Vitro Techniques
- Indoles -- administration & dosage
- Male
- Myocardial Reperfusion Injury -- blood
- Myocardium -- metabolism
- Nitric Oxide -- blood
- Nitric Oxide Synthase Type III -- genetics
- Rats, Wistar
- Receptor, Endothelin A -- genetics
- Time Factors
- Valsartan -- administration & dosage
- Vasodilation -- drug effects
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Publication Type: Comparative Study; Journal Article
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