Germline mutations affecting the histone H4 core cause a developmental syndrome by altering DNA damage response and cell cycle control. [electronic resource]
Producer: 20171102Description: 1642-1646 p. digitalISSN:- 1546-1718
- Adolescent
- Animals
- Apoptosis
- Cell Cycle Checkpoints
- Child
- DNA Damage
- DNA Repair
- Developmental Disabilities -- diagnosis
- Embryo, Nonmammalian
- Female
- Gene Expression Regulation, Developmental
- Genomic Instability
- Germ-Line Mutation
- Histones -- genetics
- Humans
- Infant
- Intellectual Disability -- diagnosis
- Microcephaly -- diagnosis
- Mutation, Missense
- Nucleosomes -- chemistry
- Syndrome
- Zebrafish -- genetics
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Publication Type: Journal Article
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