A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria. [electronic resource]
Producer: 20171121Description: 3655-3675 p. digitalISSN:- 1540-8140
- Adrenergic Fibers -- drug effects
- Anilides -- pharmacology
- Animals
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- genetics
- Axons -- drug effects
- Cells, Cultured
- Crush Injuries -- drug therapy
- Cytoprotection
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Genotype
- Mice, Inbred C57BL
- Mice, Transgenic
- Mitochondria -- drug effects
- Motor Neurons -- drug effects
- Mutation
- Neurons -- drug effects
- Neuroprotective Agents -- pharmacology
- Phenotype
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Quinolines -- pharmacology
- Rats, Sprague-Dawley
- Receptor, trkA -- antagonists & inhibitors
- Sciatic Nerve -- drug effects
- Sciatic Neuropathy -- drug therapy
- Sensory Receptor Cells -- drug effects
- Signal Transduction
- Superoxide Dismutase-1 -- genetics
- Time Factors
- Transcription, Genetic
- Wallerian Degeneration
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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