Colistin-induced autophagy and apoptosis involves the JNK-Bcl2-Bax signaling pathway and JNK-p53-ROS positive feedback loop in PC-12 cells. [electronic resource]
Producer: 20171108Description: 62-73 p. digitalISSN:- 1872-7786
- Animals
- Anti-Bacterial Agents -- toxicity
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Colistin -- toxicity
- JNK Mitogen-Activated Protein Kinases -- metabolism
- MAP Kinase Signaling System -- drug effects
- Neurons -- cytology
- PC12 Cells
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Rats
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article
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