Reversible inactivation of a peptidoglycan transpeptidase by a β-lactam antibiotic mediated by β-lactam-ring recyclization in the enzyme active site. [electronic resource]
Producer: 20190418Description: 9136 p. digitalISSN:- 2045-2322
- Acylation
- Aminoacyltransferases -- antagonists & inhibitors
- Anti-Bacterial Agents -- chemistry
- Bacterial Proteins -- antagonists & inhibitors
- Catalytic Domain -- drug effects
- Cephalosporins -- chemistry
- Cyclization
- Enterococcus faecium -- drug effects
- Mass Spectrometry
- Spectrophotometry
- beta-Lactams -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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