Safety, pharmacokinetics and dose-response characteristics of GSK2269557, an inhaled PI3Kδ inhibitor under development for the treatment of COPD. [electronic resource]
Producer: 20180612Description: 69-77 p. digitalISSN:- 1522-9629
- Administration, Inhalation
- Aged
- Class I Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
- Cytokines -- metabolism
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Forced Expiratory Volume
- Humans
- Indazoles -- administration & dosage
- Indoles
- Male
- Middle Aged
- Oxazoles -- administration & dosage
- Piperazines
- Pulmonary Disease, Chronic Obstructive -- drug therapy
- Severity of Illness Index
- Sputum -- metabolism
- Treatment Outcome
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Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
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