GSKJ4, an H3K27me3 demethylase inhibitor, effectively suppresses the breast cancer stem cells. [electronic resource]
Producer: 20171010Description: 405-414 p. digitalISSN:- 1090-2422
- Animals
- Antineoplastic Agents -- pharmacology
- Benzazepines -- pharmacology
- Cell Line, Tumor
- Enzyme Inhibitors -- pharmacology
- Female
- Gene Expression Regulation, Neoplastic
- Histone Demethylases -- antagonists & inhibitors
- Humans
- Jumonji Domain-Containing Histone Demethylases -- antagonists & inhibitors
- MCF-7 Cells
- Mice
- Mice, Nude
- Nanog Homeobox Protein -- genetics
- Neoplastic Stem Cells -- drug effects
- Nuclear Proteins -- antagonists & inhibitors
- Octamer Transcription Factor-3 -- genetics
- Pyrimidines -- pharmacology
- RNA, Small Interfering -- genetics
- SOXB1 Transcription Factors -- genetics
- Signal Transduction
- Spheroids, Cellular -- drug effects
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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