The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line. [electronic resource]
Producer: 20180905Description: 375-384 p. digitalISSN:- 1568-5608
- Adult
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- therapeutic use
- Cell Line
- Cyclooxygenase 1 -- metabolism
- Cyclooxygenase 2 -- metabolism
- Female
- Gene Expression -- drug effects
- Hexuronic Acids -- therapeutic use
- Humans
- Immunosuppressive Agents -- therapeutic use
- Inflammation -- drug therapy
- Iran
- Macrophages -- drug effects
- Male
- Mice
- Monocytes -- drug effects
- Spondylitis, Ankylosing -- drug therapy
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
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