The combination of digoxin and GSK2606414 exerts synergistic anticancer activity against leukemia in vitro and in vivo. [electronic resource]
Producer: 20180727Description: 812-820 p. digitalISSN:- 1872-8081
- Adenine -- analogs & derivatives
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Digoxin -- pharmacology
- Drug Combinations
- Drug Synergism
- Female
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Indoles -- pharmacology
- K562 Cells
- Leukemia, Erythroblastic, Acute -- drug therapy
- Mice
- Mice, Nude
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- THP-1 Cells
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.