The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells. [electronic resource]
Producer: 20180531Description: e366 p. digitalISSN:- 2092-6413
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Disease-Free Survival
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Indoles -- pharmacology
- Kaplan-Meier Estimate
- Mice
- Mice, Inbred BALB C
- Protein Kinase Inhibitors -- pharmacology
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- genetics
- Protein-Tyrosine Kinases -- metabolism
- RNA, Small Interfering -- genetics
- STAT3 Transcription Factor -- genetics
- Triple Negative Breast Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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