Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy. [electronic resource]
Producer: 20180423ISSN:- 1420-3049
- Acetylcholinesterase
- Alzheimer Disease -- drug therapy
- Aminoquinolines -- chemical synthesis
- Binding Sites
- Blood-Brain Barrier -- metabolism
- Butyrylcholinesterase
- Catalytic Domain
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cholinesterase Inhibitors -- chemistry
- Drug Design
- Drug Discovery
- Enzyme Activation -- drug effects
- Heterocyclic Compounds, 4 or More Rings -- chemistry
- Humans
- Hydrolysis
- Inhibitory Concentration 50
- Models, Molecular
- Molecular Conformation
- Molecular Structure
- Permeability
- Protein Binding
- Structure-Activity Relationship
- Tacrine -- analogs & derivatives
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Publication Type: Journal Article
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