ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. [electronic resource]
Producer: 20171102Description: 6059-6066 p. digitalISSN:- 1476-5594
- Alleles
- Animals
- Breast Neoplasms -- genetics
- Cell Line, Tumor
- Class I Phosphatidylinositol 3-Kinases -- genetics
- Disease Models, Animal
- Epithelium -- metabolism
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Mammary Glands, Animal -- metabolism
- Mammary Neoplasms, Animal -- genetics
- Mice, Transgenic
- PTEN Phosphohydrolase -- genetics
- Receptor, ErbB-2 -- genetics
- Signal Transduction
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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