Euphorbia factor L1 inhibits osteoclastogenesis by regulating cellular redox status and induces Fas-mediated apoptosis in osteoclast. [electronic resource]
Producer: 20180523Description: 191-199 p. digitalISSN:- 1873-4596
- Animals
- Apoptosis -- drug effects
- Bone Resorption
- Caspases -- genetics
- Cell Differentiation
- Diterpenes -- pharmacology
- Fas Ligand Protein -- genetics
- Female
- Gene Expression Regulation
- Macrophages -- cytology
- Male
- Mice
- Mice, Inbred C57BL
- NF-E2-Related Factor 2 -- genetics
- NF-kappa B -- genetics
- NFATC Transcription Factors -- genetics
- Osteoclasts -- cytology
- Osteogenesis -- drug effects
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha -- genetics
- Phenylpropionates -- pharmacology
- Primary Cell Culture
- Proto-Oncogene Proteins c-fos -- genetics
- RANK Ligand -- antagonists & inhibitors
- Reactive Oxygen Species -- antagonists & inhibitors
- Signal Transduction
- fas Receptor -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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