Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. [electronic resource]

By:

Yi, Bitna

Contributor(s):

Jahangir, Alam
Evans, Andrew K
Briggs, Denise
Ravina, Kristine
Ernest, Jacqueline
Farimani, Amir B
Sun, Wenchao
Rajadas, Jayakumar
Green, Michael
Feinberg, Evan N
Pande, Vijay S
Shamloo, Mehrdad

Producer: 20171023Description: e0180319 p. digitalISSN:

1932-6203

Subject(s):

Adrenergic beta-1 Receptor Agonists -- chemistry
Alzheimer Disease -- drug therapy
Animals
Brain -- metabolism
CHO Cells
Cell Line, Tumor
Cells, Cultured
Cricetinae
Cricetulus
Crystallography, X-Ray
Drug Discovery
GTP-Binding Proteins -- metabolism
Humans
Magnetic Resonance Spectroscopy
Male
Mice, Inbred C57BL
Models, Chemical
Models, Molecular
Molecular Structure
Neurocognitive Disorders -- drug therapy
Permeability
Phenyl Ethers -- chemistry
Propanolamines -- chemistry
Protein Binding
Rats, Sprague-Dawley
Receptors, Adrenergic, beta-1 -- chemistry
Structure-Activity Relationship

Online resources:

Available from publisher's website

In: PloS one vol. 12

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Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders.

APA

Yi B., Jahangir A., Evans A. K., Briggs D., Ravina K., Ernest J., Farimani A. B., Sun W., Rajadas J., Green M., Feinberg E. N., Pande V. S. & Shamloo M. (20171023). Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. : PloS one.

Chicago

Yi Bitna, Jahangir Alam, Evans Andrew K, Briggs Denise, Ravina Kristine, Ernest Jacqueline, Farimani Amir B, Sun Wenchao, Rajadas Jayakumar, Green Michael, Feinberg Evan N, Pande Vijay S and Shamloo Mehrdad. 20171023. Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. : PloS one.

Harvard

Yi B., Jahangir A., Evans A. K., Briggs D., Ravina K., Ernest J., Farimani A. B., Sun W., Rajadas J., Green M., Feinberg E. N., Pande V. S. and Shamloo M. (20171023). Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. : PloS one.

MLA

Yi Bitna, Jahangir Alam, Evans Andrew K, Briggs Denise, Ravina Kristine, Ernest Jacqueline, Farimani Amir B, Sun Wenchao, Rajadas Jayakumar, Green Michael, Feinberg Evan N, Pande Vijay S and Shamloo Mehrdad. Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. : PloS one. 20171023.

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