Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors. [electronic resource]
Producer: 20170926Description: 4553-4559 p. digitalISSN:- 1464-3391
- Acrylamides -- chemical synthesis
- Aniline Compounds
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Design
- ErbB Receptors -- antagonists & inhibitors
- Female
- Humans
- Mice
- Mice, Nude
- Mutation
- Neoplasms -- drug therapy
- Phenylenediamines -- chemical synthesis
- Piperazines -- chemistry
- Protein Kinase Inhibitors -- chemical synthesis
- Signal Transduction -- drug effects
- Transplantation, Heterologous
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Publication Type: Journal Article
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