Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor. [electronic resource]
Producer: 20170814Description: 65-73 p. digitalISSN:- 1096-0333
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Cycle Proteins -- drug effects
- Cell Proliferation -- drug effects
- Chaperonins -- drug effects
- ErbB Receptors -- antagonists & inhibitors
- Everolimus -- pharmacology
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Immunosuppressive Agents -- pharmacology
- Lung Neoplasms -- drug therapy
- Oncogene Protein v-akt -- antagonists & inhibitors
- Receptor, IGF Type 1
- Receptors, Somatomedin -- antagonists & inhibitors
- Saponins -- toxicity
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Triterpenes -- toxicity
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Publication Type: Journal Article
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