Taxifolin reduces the cholesterol oxidation product-induced neuronal apoptosis by suppressing the Akt and NF-κB activation-mediated cell death. [electronic resource]
Producer: 20180507Description: 63-71 p. digitalISSN:- 1873-2747
- Animals
- Apoptosis -- drug effects
- Caspases -- metabolism
- Cell Line, Tumor
- Cholesterol -- metabolism
- Glutathione -- metabolism
- Humans
- Ketocholesterols
- Membrane Potential, Mitochondrial -- drug effects
- NF-kappa B -- metabolism
- Neurons -- drug effects
- Neuroprotective Agents -- pharmacology
- Oxidation-Reduction -- drug effects
- PC12 Cells
- Proto-Oncogene Proteins c-akt -- metabolism
- Quercetin -- analogs & derivatives
- Rats
- Reactive Oxygen Species -- metabolism
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Publication Type: Journal Article
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