Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival. [electronic resource]
Producer: 20170919Description: 588-595 p. digitalISSN:- 1095-6859
- Age Factors
- Aged
- DNA Methylation
- DNA Mismatch Repair -- genetics
- Disease-Free Survival
- Endometrial Neoplasms -- chemistry
- Epigenesis, Genetic
- Female
- Gene Silencing
- Humans
- Lymphatic Metastasis
- Microsatellite Instability
- Middle Aged
- MutL Protein Homolog 1 -- analysis
- Mutation
- Neoplasm Grading
- Neoplasm Invasiveness -- genetics
- Neoplasm Recurrence, Local -- genetics
- Neoplasm Staging
- Tumor Burden -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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