Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency. [electronic resource]
Producer: 20170830Description: 3833-3839 p. digitalISSN:- 1464-3405
- Amides -- chemical synthesis
- Crystallography, X-Ray
- Dose-Response Relationship, Drug
- Drug Discovery
- Factor XIa -- antagonists & inhibitors
- Humans
- Macrocyclic Compounds -- chemical synthesis
- Models, Molecular
- Molecular Structure
- Serine Proteinase Inhibitors -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article
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