Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development. [electronic resource]
Producer: 20170922Description: e0180856 p. digitalISSN:- 1932-6203
- Animals
- Anticholesteremic Agents -- pharmacology
- Atorvastatin -- pharmacology
- Benzophenones -- pharmacology
- Body Patterning -- drug effects
- Cell Differentiation -- drug effects
- Cholesterol -- biosynthesis
- Chondrocytes -- drug effects
- Craniofacial Abnormalities -- genetics
- Embryo, Nonmammalian
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Developmental
- Hedgehog Proteins -- genetics
- Humans
- Hydroxymethylglutaryl CoA Reductases -- genetics
- Hydroxymethylglutaryl-CoA Synthase -- genetics
- Neural Crest -- drug effects
- Piperidines -- pharmacology
- Pyridines -- pharmacology
- Signal Transduction
- Terpenes -- antagonists & inhibitors
- Zebrafish
- Zebrafish Proteins -- genetics
- Zinc Finger Protein GLI1 -- genetics
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Publication Type: Journal Article
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