Allantopyrone A interferes with multiple components of the TNF receptor 1 complex and blocks RIP1 modifications in the TNF-α-induced signaling pathway. [electronic resource]
Producer: 20170907Description: 929-936 p. digitalISSN:- 1881-1469
- A549 Cells
- Antibiotics, Antineoplastic -- pharmacology
- Cysteine -- chemistry
- Genes, Reporter -- drug effects
- HEK293 Cells
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Molecular Weight
- NF-KappaB Inhibitor alpha -- antagonists & inhibitors
- Peptide Fragments -- antagonists & inhibitors
- Protein Interaction Domains and Motifs
- Protein Multimerization -- drug effects
- Protein Processing, Post-Translational -- drug effects
- Pyrones -- pharmacology
- Receptor-Interacting Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Receptors, Tumor Necrosis Factor, Type I -- antagonists & inhibitors
- Recombinant Fusion Proteins -- chemistry
- Signal Transduction -- drug effects
- TNF Receptor-Associated Factor 2 -- antagonists & inhibitors
- Transcription Factor RelA -- antagonists & inhibitors
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
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Publication Type: Journal Article
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