Human induced pluripotent stem cell (hiPSC)-derived neurons respond to convulsant drugs when co-cultured with hiPSC-derived astrocytes. [electronic resource]
Producer: 20170911Description: 130-138 p. digitalISSN:- 1879-3185
- Action Potentials
- Astrocytes -- metabolism
- Cell Communication
- Cell Line
- Cell Lineage
- Coculture Techniques
- Convulsants -- toxicity
- Gene Expression Profiling
- High-Throughput Nucleotide Sequencing
- Humans
- Induced Pluripotent Stem Cells -- drug effects
- Nerve Net -- drug effects
- Neural Stem Cells -- drug effects
- Neurogenesis
- Neurons -- drug effects
- Pyridazines -- toxicity
- Receptors, AMPA -- drug effects
- Receptors, N-Methyl-D-Aspartate -- drug effects
- Risk Assessment
- Scorpion Venoms -- toxicity
- Seizures -- chemically induced
- Sequence Analysis, RNA
- Single-Cell Analysis -- methods
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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