Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas. [electronic resource]
Producer: 20180109Description: 123 p. digitalISSN:- 1756-8722
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase 4 -- antagonists & inhibitors
- Drug Synergism
- Female
- Humans
- Liposarcoma -- drug therapy
- Mice
- Molecular Targeted Therapy
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-mdm2 -- antagonists & inhibitors
- Pyridines -- pharmacology
- Pyrrolidines -- pharmacology
- para-Aminobenzoates -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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