Trowaglerix Venom Polypeptides As a Novel Antithrombotic Agent by Targeting Immunoglobulin-Like Domains of Glycoprotein VI in Platelet. [electronic resource]
Producer: 20170710Description: 1307-1314 p. digitalISSN:- 1524-4636
- Animals
- Binding Sites
- Blood Platelets -- drug effects
- Carotid Artery Injuries -- blood
- Chlorides
- Computer-Aided Design
- Crotalid Venoms -- metabolism
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Design
- Ferric Compounds
- Fibrinolytic Agents -- metabolism
- Fluorescein
- Hemorrhage -- chemically induced
- Humans
- Lectins, C-Type -- metabolism
- Male
- Mice, Inbred ICR
- Molecular Docking Simulation
- Peptide Fragments -- metabolism
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- metabolism
- Platelet Membrane Glycoproteins -- antagonists & inhibitors
- Protein Binding
- Protein Interaction Domains and Motifs
- Signal Transduction -- drug effects
- Thrombosis -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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