WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. [electronic resource]
Producer: 20181119Description: 15397 p. digitalISSN:- 2041-1723
- Amino Acid Sequence
- Animals
- Animals, Newborn
- Axin Protein -- metabolism
- Base Sequence
- Cell Differentiation
- Cell Lineage
- Cell Proliferation
- Cell Self Renewal
- Ectodermal Dysplasia -- genetics
- Embryonic Development
- Epidermis -- growth & development
- Epithelium -- embryology
- Female
- Hair Follicle -- metabolism
- Humans
- Kruppel-Like Factor 4
- Kruppel-Like Transcription Factors -- metabolism
- Loss of Function Mutation -- genetics
- Male
- Mice
- Molar -- embryology
- Mutation -- genetics
- Nerve Tissue Proteins -- genetics
- Organ Specificity
- Pedigree
- Protein Binding
- Stem Cells -- metabolism
- Wnt Proteins -- genetics
- Wnt Signaling Pathway
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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