Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2. [electronic resource]
Producer: 20171004Description: 1035-1044 p. digitalISSN:- 1546-1718
- Adenosine Triphosphatases -- metabolism
- CRISPR-Cas Systems
- Charcot-Marie-Tooth Disease -- genetics
- Chromatin Assembly and Disassembly -- genetics
- Epigenetic Repression -- genetics
- Gene Silencing
- HeLa Cells
- Heterochromatin -- genetics
- Histone Code
- Histone-Lysine N-Methyltransferase
- Histones -- metabolism
- Humans
- Lysine -- chemistry
- Methylation
- Multiprotein Complexes
- Mutation, Missense
- Neurons -- metabolism
- Protein Domains
- Protein Interaction Mapping
- Protein Methyltransferases -- metabolism
- Protein Processing, Post-Translational
- Transcription Factors -- genetics
- Transgenes
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Publication Type: Journal Article
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