Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. [electronic resource]
Producer: 20181218Description: 2707 p. digitalISSN:- 2045-2322
- Animals
- Antibodies, Blocking -- pharmacology
- Central Nervous System -- immunology
- Chemokine CCL2 -- metabolism
- Dendritic Cells -- drug effects
- Encephalomyelitis, Autoimmune, Experimental -- diagnosis
- Endothelium, Vascular -- metabolism
- Immunity -- drug effects
- Lectins -- genetics
- Lectins, C-Type -- antagonists & inhibitors
- Mice
- Mice, Knockout
- Models, Biological
- Myeloid Cells -- drug effects
- Phenotype
- Protein Binding
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 -- metabolism
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- metabolism
- Receptors, Mitogen -- antagonists & inhibitors
- Recurrence
- Severity of Illness Index
- Signal Transduction
- Transendothelial and Transepithelial Migration
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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