Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions. [electronic resource]
Producer: 20181120Description: 15440 p. digitalISSN:- 2041-1723
- Antigen Presentation -- genetics
- Antigens, Neoplasm -- immunology
- Antineoplastic Agents, Immunological -- pharmacology
- Biopsy
- Cell Line, Tumor
- DNA Mutational Analysis
- Datasets as Topic
- Drug Resistance, Neoplasm -- genetics
- Histocompatibility Antigens Class I -- immunology
- Humans
- Immunotherapy -- methods
- Interferon-gamma -- immunology
- Janus Kinase 1 -- genetics
- Janus Kinase 2 -- genetics
- Melanoma -- drug therapy
- Mutation
- Mutation Rate
- Patient-Specific Modeling
- Precision Medicine -- methods
- Signal Transduction -- genetics
- Skin -- pathology
- Skin Neoplasms -- drug therapy
- T-Lymphocytes -- immunology
- Treatment Outcome
- Tumor Escape -- genetics
- Whole Genome Sequencing
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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