Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway. [electronic resource]
Producer: 20180326Description: 575-583 p. digitalISSN:- 1791-2431
- Acetylcysteine -- pharmacology
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Renal Cell -- drug therapy
- Caspase 3 -- metabolism
- Caspase 7 -- metabolism
- Caspase 9 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Chalcones -- pharmacology
- Cyclin D1 -- metabolism
- Cyclin D2 -- metabolism
- Down-Regulation
- Humans
- Janus Kinase 2 -- metabolism
- Kidney Neoplasms -- drug therapy
- NADPH Oxidases -- antagonists & inhibitors
- Onium Compounds -- pharmacology
- Phosphorylation
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-mdm2 -- metabolism
- Reactive Oxygen Species -- metabolism
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article
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