Irinotecan-temozolomide with temsirolimus or dinutuximab in children with refractory or relapsed neuroblastoma (COG ANBL1221): an open-label, randomised, phase 2 trial. [electronic resource]
Producer: 20170911Description: 946-957 p. digitalISSN:- 1474-5488
- Adolescent
- Alanine Transaminase -- blood
- Anemia -- chemically induced
- Antibodies, Monoclonal -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- adverse effects
- Camptothecin -- administration & dosage
- Child
- Child, Preschool
- Dacarbazine -- administration & dosage
- Disease-Free Survival
- Fever -- chemically induced
- Ganglioneuroblastoma -- diagnostic imaging
- Gene Amplification
- Granulocyte-Macrophage Colony-Stimulating Factor -- administration & dosage
- Humans
- Hypokalemia -- chemically induced
- Hypoxia -- chemically induced
- Infant
- Infections -- chemically induced
- Irinotecan
- N-Myc Proto-Oncogene Protein -- genetics
- Neoplasm Recurrence, Local -- diagnostic imaging
- Neuroblastoma -- diagnostic imaging
- Neutropenia -- chemically induced
- Pain -- chemically induced
- Response Evaluation Criteria in Solid Tumors
- Retreatment
- Sirolimus -- administration & dosage
- Survival Rate
- Temozolomide
- Thrombocytopenia -- chemically induced
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
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