HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival. [electronic resource]
Producer: 20180223Description: e2824 p. digitalISSN:- 2041-4889
- Animals
- Cell Count
- Cell Death -- drug effects
- Cell Survival -- drug effects
- Gene Deletion
- Hydroxymethylglutaryl CoA Reductases -- deficiency
- Integrases -- metabolism
- Lymphocyte Activation -- drug effects
- Mevalonic Acid -- analogs & derivatives
- Mice, Inbred C57BL
- Phenotype
- Polyisoprenyl Phosphates -- pharmacology
- Protein Prenylation -- drug effects
- T-Lymphocytes -- cytology
- T-Lymphocytes, Regulatory -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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