Design, synthesis and evaluation of azaacridine derivatives as dual-target EGFR and Src kinase inhibitors for antitumor treatment. [electronic resource]
Producer: 20170926Description: 372-381 p. digitalISSN:- 1768-3254
- Acridines -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Aza Compounds -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Design
- Drug Screening Assays, Antitumor
- ErbB Receptors -- antagonists & inhibitors
- Humans
- Molecular Docking Simulation
- Molecular Structure
- Protein Kinase Inhibitors -- chemical synthesis
- Structure-Activity Relationship
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article
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