Bergapten prevents lipopolysaccharide-induced inflammation in RAW264.7 cells through suppressing JAK/STAT activation and ROS production and increases the survival rate of mice after LPS challenge. [electronic resource]
Producer: 20180312Description: 159-168 p. digitalISSN:- 1878-1705
- 5-Methoxypsoralen
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Cell Survival -- drug effects
- Cyclooxygenase 2 -- metabolism
- Cytokines -- metabolism
- Janus Kinase 1 -- metabolism
- Janus Kinase 2 -- metabolism
- Lipopolysaccharides
- Male
- Methoxsalen -- analogs & derivatives
- Mice
- Mice, Inbred ICR
- Nitric Oxide Synthase Type II -- metabolism
- RAW 264.7 Cells
- Reactive Oxygen Species -- metabolism
- STAT1 Transcription Factor -- metabolism
- STAT3 Transcription Factor -- metabolism
- Shock -- drug therapy
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Publication Type: Journal Article
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