A Conserved Residue, Tyrosine (Y) 84, in H5N1 Influenza A Virus NS1 Regulates IFN Signaling Responses to Enhance Viral Infection. [electronic resource]
Producer: 20180123ISSN:- 1999-4915
- A549 Cells
- Animals
- Antiviral Agents -- pharmacology
- Disease Models, Animal
- Dogs
- Epithelial Cells -- virology
- Fibroblasts
- HEK293 Cells
- HeLa Cells
- Host-Pathogen Interactions -- drug effects
- Humans
- Influenza A Virus, H1N1 Subtype -- genetics
- Influenza A Virus, H5N1 Subtype -- metabolism
- Influenza A virus -- genetics
- Influenza, Human -- virology
- Interferon-beta
- Interferons -- drug effects
- Lung -- pathology
- Madin Darby Canine Kidney Cells
- Male
- Mice
- Mice, Inbred C57BL
- Mutagenesis, Site-Directed
- Neutrophils -- pathology
- Proto-Oncogene Proteins c-akt -- metabolism
- Reverse Genetics
- Signal Transduction -- drug effects
- Transfection
- Viral Nonstructural Proteins -- antagonists & inhibitors
- Virulence
- Virulence Factors
- Virus Diseases -- metabolism
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Publication Type: Journal Article
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