Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates. [electronic resource]
Producer: 20181211Description: 1666 p. digitalISSN:- 2045-2322
- Aged, 80 and over
- Cell Respiration
- Electron Transport
- Energy Metabolism
- Female
- Flavin-Adenine Dinucleotide -- metabolism
- Homeostasis
- Humans
- Male
- Membrane Potential, Mitochondrial
- Middle Aged
- Mitochondria -- metabolism
- Mutation -- genetics
- NAD -- metabolism
- NF-E2-Related Factor 2
- Pentose Phosphate Pathway
- Phenotype
- Reactive Oxygen Species -- metabolism
- Sequestosome-1 Protein -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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