YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation. [electronic resource]
Producer: 20170828Description: 733-743 p. digitalISSN:- 1529-2916
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- CRISPR-Cas Systems
- Cell Cycle Proteins
- Chemokine CCL5 -- genetics
- Chemokine CXCL10 -- genetics
- Fibroblasts -- immunology
- Fluorescent Antibody Technique
- Gene Editing
- HEK293 Cells
- HeLa Cells
- Humans
- I-kappa B Kinase -- metabolism
- Immunity, Innate -- immunology
- Immunoblotting
- Immunoprecipitation
- Interferon Regulatory Factor-3 -- genetics
- Interferon-beta -- genetics
- Lung -- immunology
- Lysosomes -- metabolism
- Macrophages -- immunology
- Mice
- Microscopy, Confocal
- Phosphoproteins -- genetics
- Phosphorylation
- Protein Serine-Threonine Kinases -- genetics
- RAW 264.7 Cells
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Rhabdoviridae Infections -- immunology
- Tumor Suppressor Proteins -- genetics
- Vesiculovirus
- Viral Load
- YAP-Signaling Proteins
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Publication Type: Journal Article
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