Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells. [electronic resource]
Producer: 20180309Description: 34258-34267 p. digitalISSN:- 1949-2553
- Animals
- Autophagy -- drug effects
- Bcl-2-Like Protein 11 -- genetics
- Diet, High-Fat -- adverse effects
- Disease Models, Animal
- Forkhead Box Protein O3 -- metabolism
- Gene Expression Regulation -- drug effects
- Inflammasomes -- adverse effects
- Kupffer Cells -- cytology
- Lipopolysaccharides -- adverse effects
- Mice
- NLR Family, Pyrin Domain-Containing 3 Protein -- metabolism
- Peptides, Cyclic -- adverse effects
- Transcription, Genetic
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Publication Type: Journal Article
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