Therapeutic targeting and patient selection for cancers with homologous recombination defects. [electronic resource]
Producer: 20170605Description: 565-581 p. digitalISSN:- 1746-045X
- Animals
- BRCA1 Protein -- genetics
- BRCA2 Protein -- genetics
- Breast Neoplasms -- drug therapy
- DNA Breaks, Double-Stranded
- Drug Design
- Female
- Genetic Predisposition to Disease
- Humans
- Molecular Targeted Therapy
- Mutation
- Ovarian Neoplasms -- drug therapy
- Patient Selection
- Poly(ADP-ribose) Polymerase Inhibitors -- pharmacology
- Recombinational DNA Repair -- genetics
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Publication Type: Journal Article; Review
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