Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cells. [electronic resource]
Producer: 20180309Description: 29125-29137 p. digitalISSN:- 1949-2553
- Animals
- Apoptosis
- Carcinoma, Squamous Cell -- mortality
- Carrier Proteins -- genetics
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Proliferation
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Cyclin-Dependent Kinase Inhibitor p27 -- metabolism
- Disease Progression
- Esophageal Neoplasms -- mortality
- Esophageal Squamous Cell Carcinoma
- Esophagus -- pathology
- Female
- G2 Phase Cell Cycle Checkpoints
- Gene Knockdown Techniques
- Humans
- Immunohistochemistry
- Kaplan-Meier Estimate
- Male
- Mice
- Middle Aged
- Nuclear Proteins -- metabolism
- Prognosis
- Protein-Tyrosine Kinases -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- RNA Interference
- RNA, Small Interfering -- metabolism
- Survival Rate
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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