Discovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertension. [electronic resource]
Producer: 20171219Description: 2384-2388 p. digitalISSN:- 1464-3405
- Animals
- Antihypertensive Agents -- chemical synthesis
- Aromatase Inhibitors -- chemical synthesis
- Cell Line
- Cricetulus
- Cytochrome P-450 CYP11B2 -- antagonists & inhibitors
- Cytochrome P-450 CYP2D6 Inhibitors -- chemical synthesis
- Humans
- Hypertension -- drug therapy
- Indazoles -- chemical synthesis
- Macaca mulatta
- Male
- Rats, Sprague-Dawley
- Stereoisomerism
- Steroid 11-beta-Hydroxylase -- antagonists & inhibitors
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Publication Type: Journal Article
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