A long-acting PAI-1 inhibitor reduces thrombus formation. [electronic resource]
Producer: 20180409Description: 1338-1347 p. digitalISSN:- 2567-689X
- Animals
- Bleeding Time
- Disease Models, Animal
- Drug Design
- Fibrinolysis -- drug effects
- Fibrinolytic Agents -- blood
- Half-Life
- Humans
- In Vitro Techniques
- Mice
- Mice, Inbred C57BL
- Models, Molecular
- Mutagenesis, Site-Directed
- Peptide Fragments -- pharmacology
- Plasminogen Activator Inhibitor 1 -- blood
- Protein Engineering
- Recombinant Fusion Proteins -- blood
- Serine Proteinase Inhibitors -- blood
- Serpin E2 -- antagonists & inhibitors
- Thrombosis -- prevention & control
- Urokinase-Type Plasminogen Activator -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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