Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. [electronic resource]
Producer: 20170825Description: 1413-1421 p. digitalISSN:- 1097-0134
- Amino Acid Motifs
- Aminopeptidases -- antagonists & inhibitors
- Anisoles -- chemistry
- Bacterial Proteins -- antagonists & inhibitors
- Catalytic Domain
- Cloning, Molecular
- Crystallography, X-Ray
- Cycloheptanes -- chemistry
- Epoxide Hydrolases -- chemistry
- Escherichia coli -- chemistry
- Gene Expression
- Humans
- Kinetics
- Models, Molecular
- Protease Inhibitors -- chemistry
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Conformation, beta-Strand
- Protein Interaction Domains and Motifs
- Recombinant Proteins -- chemistry
- Sequence Alignment
- Structural Homology, Protein
- Substrate Specificity
- Thermodynamics
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Publication Type: Journal Article
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