Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss. [electronic resource]
Producer: 20170420Description: 645-661 p. digitalISSN:- 1475-2662
- 3T3-L1 Cells
- AMP-Activated Protein Kinases -- metabolism
- Adipocytes -- drug effects
- Adipogenesis -- drug effects
- Animals
- Bone Marrow Cells -- cytology
- Bone Resorption -- drug therapy
- Cell Differentiation -- drug effects
- Diet, High-Fat -- adverse effects
- Disease Models, Animal
- Energy Metabolism -- drug effects
- Isoflavones -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- Obesity -- etiology
- Osteoporosis -- etiology
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Uncoupling Protein 1 -- genetics
- Up-Regulation -- drug effects
- beta Catenin -- metabolism
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Publication Type: Journal Article
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